Langerhans cell histiocytosis presenting as mandibular pain
Case report: first presentation of Langerhans cell histiocytosis with mandibular pain. Discussion of oral presentation, diagnostic issues and importance of prompt referral.
Introduction: Langerhans cell histiocytosis (LCH) is a collection of three idiopathic disorders categorised by the proliferation of specialised Langerhans cells (immature dendritic cells) and mature eosinophils.
Case report: In this paper, we demonstrate a case of a 22-year-old male patient with a complaint of persistent pain in the mandible.
Discussion: The purpose of this paper is to present a brief summary of the existing diagnostic and treatment strategies for LCH relevant to the oral and maxillofacial region, and to analyse the differential diagnosis and evaluation of these patients.
Conclusion: This case is an important reminder of the potential clinical and radiographical presentation of LCH with oral involvement, and highlights the role of the general dental practitioner in early diagnosis and prompt referral.
Journal of the Irish Dental Association December 2018/January 2019; 64 (6): 324-327.
Dr Ciara Mulvihill
NCHD, Cork University Dental School and Hospital
Dr Paul Brady
Senior Lecturer and Specialist Oral Surgeon, Cork University Dental School and Hospital
Dr Joe McKenna
Specialist Oral Surgeon, Cork University Dental School and Hospital
Prof. Duncan Sleeman
Consultant Maxillofacial Surgeon, Cork University Dental School and Hospital
Dr Sarah Ní Mhaolcatha
NCHD, Histopathology, Cork University Hospital
Corresponding author: Dr Ciara Mulvihill, Department of Oral Surgery, Cork University Dental School and Hospital, Wilton, Cork
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